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        <title>Sam Ching (@samcwl)</title>
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        <description>🤖 @Duolingo</description>
        <pubDate>Tue, 09 Aug 2022 01:00:22 GMT</pubDate>
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      <guid>https://typefully.com/samcwl/ab-testing-at-duolingo-qER6kOQ</guid>
      <title>A/B Testing at Duolingo</title>
      <description>Some folks may have seen Duolingo&#39;s viral TikToks, but not many know about how we think about product development. 

Here&#39;s how we test and iterate on products at Duolingo 🧵 We take a hypothesis driven approach and Test Everything.

Virtually all of app changes are gated and rolled out using A/B te…</description>
      <link>https://typefully.com/samcwl/ab-testing-at-duolingo-qER6kOQ</link>
      <pubDate>Tue, 09 Aug 2022 01:00:22 GMT</pubDate>
      <content:encoded><![CDATA[Some folks may have seen Duolingo's viral TikToks, but not many know about how we think about product development. <br><br>Here's how we test and iterate on products at Duolingo 🧵<br><br>We take a hypothesis driven approach and Test Everything.<br><br>Virtually all of app changes are gated and rolled out using A/B tests. <br><br><img alt="Image" src="https://api.typefully.com/media-p/03febc94-589b-4510-84c5-2139781005a2/"><br><br>(and sure, pre-empting the usual: there's a whole can of worms to be opened about hill climbing and local maximas, and would love to talk more about that, but that's for a future thread.)<br><br>First, to set context, here's an example of an A/B Test:<br><br><img alt="Image" src="https://api.typefully.com/media-p/fe1078ab-6a95-460e-9517-c6ba2cd0e8fe/"><br><br>Step 1: Have a hypothesis (a falsifiable statement) about user behavior.<br><br>We get our hypothesis from "a combination of user feedback, data from our learners, past experiment learnings, and our own intuition".<br><br>In the example above, it could be: the word "trial" triggers an alarm in our users' brains, making them less likely to try out the Super experience.<br><br>Step 2:  Test our hypothesis as rigorously as we can.<br><br>Any software makes implicit assumptions and tradeoffs about user behavior everyday. <br><br>An *opinionated* product does this especially well. <br><br>But, how do we get signal that we are making the right product calls?<br><br>Pre-Product Market Fit, we typically do it with deep user research and analytics. <br><br>Post-PMF, we do it with A/B tests at scale.<br><br>Step 3: Analyze and Call the Experiment<br><br>All product development have tradeoffs.<br><br>These can be pre-empted and discussed in the design phase. <br><br>There's sometimes a tradeoff between user retention and monetization, or monetization and learning, or user retention and learning.<br><br>But these can also be unexpected:<br><br>We have guardrails to ensure that these don't happen.<br><br>Sometimes teams can foresee this, while other times they can't and they have to dig deeper.<br><br><img alt="Image" src="https://api.typefully.com/media-p/eff6d786-2dc2-4dcc-8710-f34b4a583a49/"><br><br>Step 4: Document your learnings and socialize them.<br><br>What did you learn about user behavior? Anything unexpected? What are the key insights?<br><br>What are the next steps?<br><br>Bringing it home: our purchase flow.<br><br>You can see the evolution in our thinking here. <br><br>Over the years, you can see:<br><br>Hypotheses of...<br><br>testing clear upfront pricing, <br><br><img alt="Image" src="https://api.typefully.com/media-p/78e009f6-be67-4511-a29d-bfcd091fc794/"><br><br>reducing choice, <br>calling out user benefits, <br><br><img alt="Image" src="https://api.typefully.com/media-p/accaef54-cf02-4a31-bca0-35c313819160/"><br><br>testing redesigns (both of Duo and the app!)<br><br>(shoutout to our tireless Monetization Area's work on this)<br><br><img alt="Image" src="https://api.typefully.com/media-p/6fbce506-9629-4c0a-9947-a7ef0dd5f343/"><br><br>If interested, read more here in our latest shareholder letter and listen to the shareholder call with <a class="tweet-url username" href="https://twitter.com/luisvonahn" data-screen-name="luisvonahn" target="_blank" rel="nofollow">@luisvonahn</a> and Matt Skaruppa.<br><br><a href="https://investors.duolingo.com/" target="_blank" rel="nofollow">https://investors.duolingo.com/</a><br><br>Also see more examples of past experiments on our blog <br><br>(<a href="https://blog.duolingo.com/how-duolingo-streak-builds-habit/" target="_blank" rel="nofollow">https://blog.duolingo.com/how-duolingo-streak-builds-habit/</a>) <br><br>Future threads coming about how our experimentation team built this, what we learned along the way, and where we are going.<br><br>Oh and Duolingo is still hiring! <br><br>Come work with folks who are the best in the business <a class="tweet-url username" href="https://twitter.com/cemkansu" data-screen-name="cemkansu" target="_blank" rel="nofollow">@cemkansu</a> <a class="tweet-url username" href="https://twitter.com/Albertc248" data-screen-name="Albertc248" target="_blank" rel="nofollow">@Albertc248</a> <a class="tweet-url username" href="https://twitter.com/nickeyskarstad" data-screen-name="nickeyskarstad" target="_blank" rel="nofollow">@nickeyskarstad</a> and many more!<br><br><a href="https://careers.duolingo.com/" target="_blank" rel="nofollow">https://careers.duolingo.com/</a><br><br>You can read the unrolled version of this thread here: <a href="https://typefully.com/samcwl/qER6kOQ" target="_blank" rel="nofollow">https://typefully.com/samcwl/qER6kOQ</a>]]></content:encoded>
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      <guid>https://typefully.com/samcwl/tcm-lessgreater-western-drug-interactions-NNnnrq3</guid>
      <title>TCM &lt;&gt; Western Drug interactions</title>
      <description>TIL: Not much is known about the herb-drug interaction between TCM (traditional chinese medicine) and western drugs (i.e. Aspirin).

🧵: 1/ Apart from spacing out the dosage times (~2h in between), there&#39;s not much known about how to think about the pharmacodynamic interactions between these classes…</description>
      <link>https://typefully.com/samcwl/tcm-lessgreater-western-drug-interactions-NNnnrq3</link>
      <pubDate>Sun, 24 Jul 2022 22:52:58 GMT</pubDate>
      <content:encoded><![CDATA[TIL: Not much is known about the herb-drug interaction between TCM (traditional chinese medicine) and western drugs (i.e. Aspirin).<br><br>🧵:<br><br>1/ Apart from spacing out the dosage times (~2h in between), there's not much known about how to think about the pharmacodynamic interactions between these classes of drugs.<br><br>2/ As someone currently experiencing flu-like symptoms, I rotate my symptom management between western drugs, traditional western herbal remedies (echinacea, ginger, turmeric) and traditional chinese medicine (TCM). <br><br>3/ However, just as how you should not take some drugs with others, I'm also curious about herb-drug interactions.<br><br>4/ However, while some work has been done looking at the former two, there's not much work that has been done between the first and the last.<br><br><img alt="Image" src="https://api.typefully.com/media-p/f0e0e9e0-a5bc-4e23-afb3-63359fdf566f/"><br><br>5/ Have also found this database (<a href="http://naturaldatabaseconsumer.therapeuticresearch.com/" target="_blank" rel="nofollow">http://naturaldatabaseconsumer.therapeuticresearch.com/</a>) to be somewhat useful, but since the search space is n^2, chances are that studies for a specific herb-drug combination is studied is low, especially among TCM - western drugs.<br><br>6/ So, drug-addled me came across this paper in the Singapore Medical Journal today:<br><br><img alt="Image" src="https://api.typefully.com/media-p/eca0fd4e-2962-40b4-8efc-d88417672436/"><br><br> While this paper is pretty dated (and the data pull comes from studies published pre Dec 2013), it provides some valuable ways to think about herb-drug interaction and TCM for me:<br><br>1. Differences between Pharmacokinetic vs Pharmacodynamics Interactions.<br><br><img alt="Image" src="https://api.typefully.com/media-p/21a53396-7ea3-44ab-85bb-0ed60129a612/"><br><br>TCM herbs and Aspirin tend not to have a Pharmacokinetic effect (but SG drs still recommend you take them ~2h apart), rather they could have pharamacodynamic interactions.<br><br>7/ 2. There's an entire class of herbs in Chinese which promote syndromes of Qi / increases blood circulation<br><br><img alt="Image" src="https://api.typefully.com/media-p/19b5e7ef-40c0-4d0a-80f7-f09c8fe4c991/"><br><br>8/ 3. Many of the studies (at least when this paper was published) are in animals and in-vitro, not in-vivo RCTs. <br><br>As with any herb, methods of preparation, provenance, concentration and dosage all affect bodily ingestion.<br><br><img alt="Image" src="https://api.typefully.com/media-p/c31632d4-432c-495d-ac1e-7b58ffc9cf2f/"><br><br>9/ 4. TCM practitioners often "stack" herbs to boost efficacy (would sound familiar to the nootropic gang). This compounding effect of herbs is also not well documented.<br><br><img alt="Image" src="https://api.typefully.com/media-p/e83ff444-0e35-4bfc-94db-d524524c8bc6/"><br><br>10/ So, would I still consume my herbs? <br><br>Yes - hard to shake away that part of me - but definitely will try to be more aware of the specifics of the herbs and try to understand their mechanisms before scaling the dosage.<br><br>11/ Final thought: the general UX of this space is pretty bad. <br><br>Low hanging fruit for a CRUD app where you could list all your current medications and it'll ping the DBs for any known pairwise interactions.<br><br>This could be more important in the coming years with the "mainstreaming" of more herbal remedies (adaptogens and nootropics)<br><br>You can read the unrolled version of this thread here: <a href="https://typefully.com/samcwl/NNnnrq3" target="_blank" rel="nofollow">https://typefully.com/samcwl/NNnnrq3</a>]]></content:encoded>
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